Description
Peptide Profile
KPV (Lysine–Proline–Valine) is a synthetic tripeptide and the active C-terminal fragment of α-melanocyte stimulating hormone (α-MSH). Compact yet robust, KPV provides significant anti-inflammatory, antimicrobial, and immune-modulating advantages. It soothes cytokine activity, safeguards barrier tissues such as skin and gut, and accelerates healing — making it a reliable peptide for athletes, wellness advocates, and anyone aiming to enhance recovery and resilience.
Peptide Name: KPV (Lys-Pro-Val), α-MSH(11–13)
CAS Number (free acid): 67727-97-3 (variant Ac-KPV-NH2: CAS 112965-21-6)
Molecular Formula (free acid): C16H30N4O4
Molecular Weight (free acid): 342.43 g/mol
Main Function: Powerful anti-inflammatory and immune-modulating tripeptide
Mechanism of Action: Reduces pro-inflammatory cytokines (TNF-α, IL-1β, IL-6), lessens immune cell infiltration, boosts tissue repair, and fortifies antimicrobial defense. Uptake occurs through PepT1 transporters, guaranteeing robust effects in gut and barrier tissues.
The Amino Acid Advantage
- Lysine (K): Essential for tissue repair, antibody and enzyme production, and maintenance of immune balance. In KPV, Lysine is pivotal in modulating inflammatory responses.
- Proline (P): A structural amino acid that stabilizes proteins. Proline ensures KPV retains the correct conformation to effectively interact with cellular targets.
- Valine (V): A branched-chain amino acid crucial for protein synthesis and energy metabolism. Valine aids in the cellular absorption of KPV and enhances its biological impact.
Key Features & Benefits
- Decreases inflammation by silencing cytokine activity
- Balances immune responses and mitigates autoimmune triggers
- Promotes skin health and barrier protection (psoriasis, eczema, dermatitis)
- Speeds up wound healing and tissue regeneration
- Alleviates pain associated with inflammatory processes
- Preserves gut lining and promotes intestinal health in IBD situations
- Offers antimicrobial protection against specific pathogens
- Boosts recovery and overall vitality for anti-aging benefits
Best For:
- Athletes recovering from rigorous training or injuries
- Biohackers and longevity enthusiasts concentrating on anti-aging and systemic wellness
- Individuals managing gut problems or skin disorders
- Anyone looking to alleviate chronic inflammation and enhance daily resilience
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